Ketotifen in the management of chronic urticaria: resurrection of an old drug

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Ketotifen in the management of chronic urticaria: resurrection of an old drug.

Ketotifen is an oral antiallergic drug developed in 1970 by Sandoz Pharmaceuticals of Switzerland. It is a benzocycloheptathiophene derivative and was initially marketed as an inhibitor of anaphylaxis.1 The pharmacodynamic properties of ketotifen are many, because it is an inhibitor of the release and/or activity of mast cell and basophil mediators, including histamine, neutrophil, and eosinoph...

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ژورنال

عنوان ژورنال: Annals of Allergy, Asthma & Immunology

سال: 2013

ISSN: 1081-1206

DOI: 10.1016/j.anai.2013.10.003